Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(35)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(51)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(6)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(300)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(21)
- PLK(51)
- PTEN(7)
- Wee1(15)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(71)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
Products Related to Cell Cycle/Checkpoint(1536)
- GC49532S-(1,2-Dichlorovinyl)-Cysteine (hydrochloride)CAS: 2508026-62-6Purity: >95.00%
A nephrotoxin and metabolite of trichloroethylene
- GC49547L-Glutamic Acid γ-p-Nitroanilide (hydrate)CAS: 122864-94-2Purity: >95.00%
A colorimetric substrate for γ-glutamyl transpeptidase
- GC49674SchizandrinCAS: 7432-28-2Purity: >97.00%
Schizandrin (Schizandrin), ein Dibenzocyclooctadien-Lignan, wird aus der Frucht von Schisandra chinensis Baill isoliert.
- GC49682Dabigatran-d3CAS: 1246817-44-6Purity: >99.00%
An internal standard for the quantification of dabigatran
- GC49684Dabigatran-13C-d3CAS: 2967480-55-1Purity: >99.00%
An internal standard for the quantification of dabigatran
- GC49685Trifluoroacetyl Tripeptide-2 (acetate)Purity: >98.00%
A peptide inhibitor of pancreatic and neutrophil elastases
- GC49690(3R,5R)-Rosuvastatin (calcium salt)CAS: 1422515-55-6Purity: >95.00%
A potential impurity found in bulk preparations of rosuvastatin
- GC49723SenTraGor™ Cell Senescence ReagentCAS: 2171036-89-6Purity: >95.00%
A cellular senescence detection reagent
- GC4973610-acetyl DocetaxelCAS: 125354-16-7Purity: >98.00%
10-Acetyl-Docetaxel (10-Acetyl-Docetaxel) ist ein Analogon von Docetaxel mit AntikrebsaktivitÄt. Docetaxel ist ein Inhibitor der Mikrotubuli-Zerlegung mit antimitotischer AktivitÄt.
- GC49740Brevetoxin 3CAS: 85079-48-7Purity: >95.00%
Brevetoxin 3 (PbTx-3) ist ein starker allosterischer spannungsgesteuerter Na+-Kanalaktivator und hat mehrere aktive Zentren (A-Ring-Lacton, C-42 der R-Seitenkette).
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49532 | S-(1,2-Dichlorovinyl)-Cysteine (hydrochloride) | 2508026-62-6 | >95.00% | |
A nephrotoxin and metabolite of trichloroethylene | ||||
| GC49547 | L-Glutamic Acid γ-p-Nitroanilide (hydrate) | 122864-94-2 | >95.00% | |
A colorimetric substrate for γ-glutamyl transpeptidase | ||||
| GC49605 | H-Gly-Pro-Hyp-OH (acetate) | 103192-50-3 | >95.00% | |
A peptide DPP-4 inhibitor | ||||
| GC49671 | 2,3-Oxidosqualene | 7200-26-2 | >90.00% | |
An intermediate in the biosynthesis of sterols | ||||
| GC49674 | Schizandrin | 7432-28-2 | >97.00% | |
Schizandrin (Schizandrin), ein Dibenzocyclooctadien-Lignan, wird aus der Frucht von Schisandra chinensis Baill isoliert. | ||||
| GC49682 | Dabigatran-d3 | 1246817-44-6 | >99.00% | |
An internal standard for the quantification of dabigatran | ||||
| GC49684 | Dabigatran-13C-d3 | 2967480-55-1 | >99.00% | |
An internal standard for the quantification of dabigatran | ||||
| GC49685 | Trifluoroacetyl Tripeptide-2 (acetate) | - | >98.00% | |
A peptide inhibitor of pancreatic and neutrophil elastases | ||||
| GC49687 | Goralatide (acetate) | - | >95.00% | |
A tetrapeptide regulator of hematopoiesis | ||||
| GC49690 | (3R,5R)-Rosuvastatin (calcium salt) | 1422515-55-6 | >95.00% | |
A potential impurity found in bulk preparations of rosuvastatin | ||||
| GC49695 | FKBP52 Monoclonal Antibody (Clone Hi52C) | - | - | |
For immunochemical analysis of FKBP52 | ||||
| GC49699 | Acetyl Tetrapeptide-9 (acetate) | - | >95.00% | |
A synthetic signal peptide | ||||
| GC49702 | Papain Inhibitor (trifluoroacetate salt) | - | >95.00% | |
A peptide inhibitor of papain | ||||
| GC49704 | Ac-FLTD-CMK (trifluoroacetate salt) | - | >95.00% | |
An inhibitor of caspase-1, -4, -5, and -11 | ||||
| GC49709 | cyclo(RGDyC) (trifluoroacetate salt) | - | >98.00% | |
A cyclic pentapeptide | ||||
| GC49713 | SIKVAV (acetate) | - | >98.00% | |
A laminin α1-derived peptide | ||||
| GC49723 | SenTraGor™ Cell Senescence Reagent | 2171036-89-6 | >95.00% | |
A cellular senescence detection reagent | ||||
| GC49724 | BIO-1211 (trifluoroacetate salt) | - | >98.00% | |
A peptide inhibitor of α4β1 integrin | ||||
| GC49735 | Thallos AM | 1802991-71-4 | >95.00% | |
A cell-permeable fluorescent thallium indicator | ||||
| GC49736 | 10-acetyl Docetaxel | 125354-16-7 | >98.00% | |
10-Acetyl-Docetaxel (10-Acetyl-Docetaxel) ist ein Analogon von Docetaxel mit AntikrebsaktivitÄt. Docetaxel ist ein Inhibitor der Mikrotubuli-Zerlegung mit antimitotischer AktivitÄt. | ||||
| GC49740 | Brevetoxin 3 | 85079-48-7 | >95.00% | |
Brevetoxin 3 (PbTx-3) ist ein starker allosterischer spannungsgesteuerter Na+-Kanalaktivator und hat mehrere aktive Zentren (A-Ring-Lacton, C-42 der R-Seitenkette). | ||||
| GC49742 | Hsf1 Monoclonal Antibody (Clone 10H8) | - | - | |
For immunochemical analysis of Hsf1 | ||||
| GC49744 | GRP94 Monoclonal Antibody (Clone 9G10) | - | - | |
For immunochemical detection of GRP94 | ||||
| GC49751 | Lefamulin | 1061337-51-6 | >95.00% | |
Lefamulin (BC-3781) ist ein oral wirksames Antibiotikum. | ||||