S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate |
| Katalog-Nr.GC61257 |
S-(1-Hydroxy-2-methylpropan-2-yl)methansulfonothioat ist ein durch Glutathion spaltbarer ADC-Linker, der fÜr die AntikÖrper-Wirkstoff-Konjugate (ADCs) verwendet wird und sich auf die Alkylketten-Zusammensetzung bezieht. S-(1-Hydroxy-2-methylpropan-2-yl)methansulfonothioat sind die Linker-Teile der MolekÜle, die fÜr mAb-Anheftungszwecke verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2127875-65-2
Sample solution is provided at 25 µL, 10mM.
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S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].
[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.
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