Spiraeoside |
| Katalog-Nr.GC64234 |
Spiraeosid, eine oral aktive natÜrliche Verbindung, Übt antioxidative AktivitÄt aus, hemmt reaktive Sauerstoffspezies (ROS) und die Produktion von Malondialdehyd.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 20229-56-5
Sample solution is provided at 25 µL, 10mM.
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Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities[1].
Spiraeoside elevates HG stimulation-caused the decrease in the expression levels of p-Akt, nuclear Nrf2, and HO-1 in AC16 cells (the effects of Spiraeoside are reversedby LY294002)[1]. Spiraeoside protects AC16 cells against HG-induced oxidative stress, cell injury, and apoptosis[1]. Spiraeoside activates the PI3K/Akt/Nrf2 pathway in AC16 cells on exposure to HG[1].Spiraeoside protects AC16 cells against HG-induced apoptosis through the PI3K/Akt/Nrf2 pathway[1].
Spiraeoside (50 mg/kg, p.o.) shows ulcer preventive ability[2].
[1]. Hongyang Liu, et al. Spiraeoside protects human cardiomyocytes against high glucose-induced injury, oxidative stress, and apoptosis by activation of PI3K/Akt/Nrf2 pathway. J Biochem Mol Toxicol. 2020 Oct;34(10):e22548.
[2]. Stevan Samard?i?, et al. Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench. J Ethnopharmacol. 2018 Mar 1;213:132-137.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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