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Tetradecylphosphocholine (Synonyms: Fos-choline 14)

Katalog-Nr.GC18340

Tetradecylphosphocholine is a zwitterionic surfactant.

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Tetradecylphosphocholine Chemische Struktur

Cas No.: 77733-28-9

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Sample solution is provided at 25 µL, 10mM.

Description of Tetradecylphosphocholine

Tetradecylphosphocholine is a zwitterionic surfactant. It has been used in the solubilization and purification of G protein-coupled receptors (GPCRs). It has also been used as the stationary phase in ion chromatography for the determination of inorganic acids. Tetradecylphosphochline has a critical micelle concentration (CMC) of approximately 0.12 mM.

Chemical Properties of Tetradecylphosphocholine

Cas No. 77733-28-9 SDF
Überlieferungen Fos-choline 14
Chemical Name 2-[[hydroxy(tetradecyloxy)phosphinyl]oxy]-N,N,N-trimethyl-ethanaminium, inner salt
Canonical SMILES C[N+](C)(C)CCOP(OCCCCCCCCCCCCCC)([O-])=O
Formula C19H42NO4P M.Wt 379.5
Löslichkeit DMF: 16 mg/ml,DMSO: 16 mg/ml,Ethanol: 15 mg/ml,PBS (pH 7.2): 25 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Tetradecylphosphocholine

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.635 mL 13.1752 mL 26.3505 mL
5 mM 0.527 mL 2.635 mL 5.2701 mL
10 mM 0.2635 mL 1.3175 mL 2.635 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of Tetradecylphosphocholine

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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