TSPC |
| Katalog-Nr.GC52066 |
TSPC ist ein Wahrnehmungshemmer des Phytohormons Gibberellin (GA) mit einem IC50-Wert von 10 μM in vitro.
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Cas No.: 882286-32-0
Sample solution is provided at 25 µL, 10mM.
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TSPC is an inhibitor of the gibberellin receptor GID1.1 It inhibits the gibberellin-induced interaction between the gibberellin receptor GID1 and a negative regulator of its signaling, DELLA, in a yeast two-hybrid assay (IC50 = <30 µM) and gibberellin binding to GID1 in the presence or absence of DELLA in a cell-free assay when used at concentrations ranging from 1 to 100 µM. TSPC (10-100 µM) suppresses seed germination and seedling growth in Arabidopsis.
1.Yoon, J.-M., Nakajima, M., Mashiguchi, K., et al.Chemical screening of an inhibitor for gibberellin receptors based on a yeast two-hybrid systemBioorg. Med. Chem. Lett.23(4)1096-1098(2013)
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