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VU6012962

Katalog-Nr.GC34320

VU6012962 ist ein oral bioverfÜgbarer und ZNS-penetranter metabotroper Glutamatrezeptor 7 negativer allosterischer Modulator (mGlu7 NAM) mit einem IC50 von 347 nM.

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VU6012962 Chemische Struktur

Cas No.: 2313526-86-0

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 (mGlu7) negative allosteric modulator (NAM) with an IC50 of 347 nM[1].

[1]. Reed CW, et al. Discovery of an orally bioavailable and Central Nervous System (CNS) penetrant mGlu7 NegativeAllosteric Modulator (NAM) in vivo tool compound: N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU6012962). J Med Chem. 2019 Jan 4.

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Average Rating: 5 ★★★★★ (Based on Reviews and 3 reference(s) in Google Scholar.)

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