(±)-Cloprostenol sodium salt (Synonyms: (±)16mchlorophenoxy tetranor PGF2α, (±)16mchlorophenoxy tetranor Prostaglandin F2α, DLCloprostenol) |
| Catalog No.GC16838 |
(±)-Le sel de sodium de cloprosténol (sel de sodium ICI 80996) est un puissant analogue synthétique de la prostaglandine, agit comme un agent lutéolytique et est un agoniste du récepteur PGF2α.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 55028-72-3
Sample solution is provided at 25 µL, 10mM.
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Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent[1], and is a PGF2α receptor agonist[2].
Cloprostenol is a PGF2α receptor agonist[2].Cloprostenol (0.1 μM) counteracts the adipogenic effects of statil, on both intracellular lipid accumulation and expression of transcripts for proadipogenic factors C/EBPα and PPARγ after treatment for 6 days[2].
Cloprostenol sodium salt (25 μg) decreases plasma progesterone in pregnant rats[1].
References:
[1]. Salazar H, et al. Luteolytic effects of a prostaglandin analogue, cloprostenol (ICI 80,996), in rats: ultrastructural and biochemical observations. Biol Reprod. 1976 May;14(4):458-72.
[2]. Pastel E, et al. Aldose reductases influence prostaglandin F2α levels and adipocyte differentiation in male mouse and human species. Endocrinology. 2015 May;156(5):1671-84.
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