Ferutinin |
| Catalog No.GC18641 |
La ferutinine, un composé terpénoÏde naturel, est un agoniste des récepteurs ERα des œstrogènes et un agoniste/antagoniste des récepteurs ERβ des œstrogènes avec des CI50 de 33,1 nM et 180,5 nM, respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 41743-44-6
Sample solution is provided at 25 µL, 10mM.
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Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) α (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM). It also demonstrates ionophoretic properties, increasing calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes at a concentration range of 1-50 uM. Ferutinin is cytotoxic to MCF-7 breast and TCC bladder cancer cells as well as human foreskin HFF3 fibroblasts (IC50s = 29, 24, and 36 ug/ml in vitro after 72 hours of exposure).
Review for Ferutinin
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
Review for Ferutinin
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