Ferutinin |
| カタログ番号GC18641 |
天然のテルペノイド化合物であるフェルチニンは、それぞれ 33.1 nM および 180.5 nM の IC50 を持つエストロゲン受容体 ERα アゴニストおよびエストロゲン ERβ 受容体アゴニスト/アンタゴニストです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 41743-44-6
Sample solution is provided at 25 µL, 10mM.
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Ferutinin is a plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for estrogen receptor (ER) α (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM). It also demonstrates ionophoretic properties, increasing calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes at a concentration range of 1-50 uM. Ferutinin is cytotoxic to MCF-7 breast and TCC bladder cancer cells as well as human foreskin HFF3 fibroblasts (IC50s = 29, 24, and 36 ug/ml in vitro after 72 hours of exposure).
Review for Ferutinin
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
Review for Ferutinin
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