FAK ligand-Linker Conjugate 1 |
| Catalog No.GC38127 |
FAK ligand-Linker Conjugate 1 incorpore un ligand pour FAK et un lieur PROTAC, qui recrutent des ligases E3 (telles que VHL, CRBN, MDM2 et IAP). FAK ligand-Linker Conjugate 1 peut être largement utilisé pour la dégradation des protéines médiée par PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2307461-45-4
Sample solution is provided at 25 µL, 10mM.
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FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1].
[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.
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