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Accueil >> Signaling Pathways >> Cancer Biology

Cancer Biology

Products for  Cancer Biology

  1. Cat.No. Nom du produit Informations
  2. GP10141 Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]

    H2N-Phe-Leu-Asp-Pro-Arg-Pro-Leu-Thr-Val-OH

    Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] Chemical Structure
  3. GC43361 Cytostatin (sodium salt) Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. Cytostatin (sodium salt) Chemical Structure
  4. GC43368 D,L-1′-Acetoxychavicol Acetate

    ACA, 1'-Acetoxychavicol Acetate, Galangal Acetate

     D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. D,L-1′-Acetoxychavicol Acetate Chemical Structure
  5. GC43504 D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt)

    IP6, Phytic Acid

     L'acide phytique (Inositol hexaphosphate) hexasodique est un composé de stockage du phosphore des graines et des céréales. D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt) Chemical Structure
  6. GC47168 Daidzein-d4 An internal standard for the quantification of daidzein Daidzein-d4 Chemical Structure
  7. GC60121 Dasatinib D8

    Sprycel-d8

     Dasatinib D8 est un Dasatinib marqué au deutérium. Le dasatinib est un inhibiteur de tyrosine kinase de la famille double Bcr-Abl et Src. Dasatinib D8 Chemical Structure
  8. GC48581 Daunorubicinone

    (+)-Daunomycinone, NSC 109531

     An aglycone form of daunorubicin Daunorubicinone Chemical Structure
  9. GC40697 DDA

    Decadienealdehyde, trans2,4Decadien1al

     Le DDA est un produit de peroxydation lipidique de l'acide linoléique. DDA Chemical Structure
  10. GC43390 Deacetylravidomycin Deacetylravidomycin is a microbial metabolite that has been found in Streptomyces and has light-dependent antibiotic and anticancer activities. Deacetylravidomycin Chemical Structure
  11. GC43391 Decanoic Acid (sodium salt)

    C10:0, Capric Acid, Decylic Acid

     Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons. Decanoic Acid (sodium salt) Chemical Structure
  12. GC45815 Decanoic Acid-d19

    Capric Acid-d19, Decylic Acid-d19

     An internal standard for the quantification of decanoic acid Decanoic Acid-d19 Chemical Structure
  13. GC46127 Decanoic Acid-d2

    C10:0-d2, Capric Acid-d2, Decylic Acid-d2

     An internal standard for the quantification of decanoic acid Decanoic Acid-d2 Chemical Structure
  14. GC45722 Decanoic Acid-d3

    Capric Acid-d3, Decylic Acid-d3

     An internal standard for the quantification of decanoic acid Decanoic Acid-d3 Chemical Structure
  15. GC40230 Deferasirox-d4 Deferasirox-d4 est le deutérium marqué Deferasirox. Le déférasirox (ICL 670) est un chélateur du fer disponible par voie orale utilisé pour la gestion de la surcharge en fer transfusionnelle. Deferasirox-d4 Chemical Structure
  16. GC52316 Deferitrin

    GT-56-252, (S)-4'-Hydroxydesazadesferrithiocin

     An iron chelator and derivative of desferrithiocin Deferitrin Chemical Structure
  17. GC40654 Deoxyviolacein Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein that has anticancer, antibacterial, and antifungal properties. Deoxyviolacein Chemical Structure
  18. GC47211 Dichlorvos

    DDVP, Dichlorovinyl Dimethyl Phosphate, NSC 6738

     An organophosphate insecticide Dichlorvos Chemical Structure
  19. GC49293 Dichlorvos-d6

    DDVP-d6, Dichlorovinyl Dimethyl Phosphate-d6

     An internal standard for the quantification of dichlorvos Dichlorvos-d6 Chemical Structure
  20. GC47215 Dienogest-d8 An internal standard for the quantification of dienogest Dienogest-d8 Chemical Structure
  21. GC52194 Dimethylamino Parthenolide

    DMAPT, LC-1

     Dimethylamino Parthenolide Chemical Structure
  22. GC49383 DL-Phenyl-d5-alanine

    (±)-Phenyl-d5-alanine

     An internal standard for the quantification of DL-phenylalanine DL-Phenyl-d5-alanine Chemical Structure
  23. GC18254 DM1-SMe DM1-SMe est une forme non conjuguée du MaytansinoÏde dans IMGN901. Le DM1-SMe est environ 3 À 10 fois plus puissant que le médicament parent Maytansine, avec des IC50 allant de 0,003 À 0,01 nM pour le DM1-SMe dans un panel de lignées cellulaires tumorales humaines. DM1-SMe Chemical Structure
  24. GC48968 Docetaxel (hydrate)

    DTX, NSC 628503, RP 56976, Taxotel

    An analog of taxol with antitumor properties

     Docetaxel (hydrate) Chemical Structure
  25. GC47250 Docetaxel-d9

    DTX-d9, Taxotel-d9

     Le docétaxel-d9 (RP-56976-d9) est le docétaxel marqué au deutérium. Le docétaxel (RP-56976) est un inhibiteur de la dépolymérisation des microtubules, avec une IC50 de 0,2μM. Le docétaxel atténue les effets de l'expression des gènes bcl-2 et bcl-xL. Le docétaxel arrête le cycle cellulaire À G2/M et conduit À l'apoptose cellulaire. Le docétaxel a une activité anticancéreuse. Docetaxel-d9 Chemical Structure
  26. GC40082 Drimentine B Drimentine B is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. Drimentine B Chemical Structure
  27. GC43573 Drimentine C Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. Drimentine C Chemical Structure
  28. GC49001 DSPE-PEG(2000)-amine (sodium salt) A PEGylated derivative of DSPE DSPE-PEG(2000)-amine (sodium salt) Chemical Structure
  29. GC52333 DSPE-PEG(2000)-NHS

    DSPE-PEG(2000)-NHS is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE .

     DSPE-PEG(2000)-NHS Chemical Structure
  30. GC49058 DTPA

    Diethylenetriaminepentaacetic Acid, NSC 7340, Pentetic Acid

     Le DTPA est un composé utilisé pour construire un adsorbant magnétique, qui peut simultanément éliminer les métaux lourds et les colorants des eaux usées complexes. DTPA Chemical Structure
  31. GC18992 Duclauxin

    NSC 258308

     Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. Duclauxin Chemical Structure
  32. GP10022 Dynamin inhibitory peptide

    Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro

    Dynamin inhibitory peptide Chemical Structure
  33. GC65123 Eclalbasaponin I L'eclalbasaponine I est isolée d'Eclipta prostrata L avec une activité antitumorale. L'eclalbasaponine I inhibe la prolifération des cellules d'hépatome smmc-7721 avec une valeur IC50 de 111,1703 μg/ml. Eclalbasaponin I Chemical Structure
  34. GP10030 EGF receptor substrate eps15 acetyl - [Mus musculus]/[Homo sapiens]

    Ac-Gln-Glu-Gln-Glu-Asp-Leu-Glu-Leu-Ala-Ile-Ala-Leu-Ser-Lys-Ser-Glu-Ile-Ser-Glu-Ala-OH

    EGF receptor substrate eps15 (Eps15) has been identified as a 142-kDa substrate of the EGF receptor1. EGF receptor substrate eps15 acetyl - [Mus musculus]/[Homo sapiens] Chemical Structure
  35. GP10108 EGF-R (661-681) T669 Peptide

    H2N-Lys-Arg-Glu-Leu-Val-Glu-Pro-Leu-Thr-Pro-Ser-Gly-Glu-Ala-Pro-Asn-Gln-Ala-Leu-Leu-Arg-OH

    EGF-R (661-681) T669 Peptide Chemical Structure
  36. GC43591 Eicosapentaenoyl 1-propanol-2-amide Monoacylglycerols (MAGs) of ω-3 polyunsaturated fatty acids have diverse physiological and health effects. Eicosapentaenoyl 1-propanol-2-amide Chemical Structure
  37. GC49522 EM-12

    EM-12

     L'EM-12 (EM-12), un analogue tératogène de la thalidomide, est plus actif que la thalidomide et est beaucoup plus stable À l'hydrolyse. EM-12 améliore l'induction par la 1,2-diméthylhydrazine des adénocarcinomes du cÔlon de rat. EM-12 Chemical Structure
  38. GC46137 Emestrin A mycotoxin Emestrin Chemical Structure
  39. GC49124 EN219 EN219 est un ligand covalent synthétique modérément sélectif contre une cystéine N-terminale (C8) de RNF114 avec une IC50 de 470 nM. EN219 inhibe l'auto-ubiquitination médiée par RNF114 et l'ubiquitination p21. EN219 Chemical Structure
  40. GP10117 Endostatin (84-114)-NH2 (JKC367)

    H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2

    Endostatin (84-114)-NH2 (JKC367) Chemical Structure
  41. GC49648 Enobosarm-d4

    (S)-Enobosarm-d4

     An internal standard for the quantification of enobosarm Enobosarm-d4 Chemical Structure
  42. GC47297 EP4 Receptor Antagonist 1 L'antagoniste du récepteur EP4 1 est un antagoniste du récepteur prostanoÏde EP4 compétitif très puissant et sélectif pour l'immunothérapie du cancer. EP4 Receptor Antagonist 1 Chemical Structure
  43. GP10005 Epidermal growth factor receptor (994-1002) acetyl/amide

    Ac-Asp-Ser-Asn-Phe-Tyr-Arg-Ala-Leu-Met-amide

    EGF-family receptor

     Epidermal growth factor receptor (994-1002) acetyl/amide Chemical Structure
  44. GP10095 Epidermal Growth Factor Receptor Peptide (985-996)

    H2N-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH

    Epidermal Growth Factor Receptor Peptide (985-996) Chemical Structure
  45. GP10132 erbB-2

    H2N-Lys-Ile-Phe-Gly-Ser-Leu-Ala-Phe-Leu-OH

    erbB-2 Chemical Structure
  46. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil Ethyl Mycophenolate Chemical Structure
  47. GC15555 Farnesyl Thiosalicylic Acid Amide

    FTS Amide,Salirasib Amide

     inhibits tumor growth Farnesyl Thiosalicylic Acid Amide Chemical Structure
  48. GP10123 Fas C- Terminal Tripeptide

    Ac-Ser-Leu-Val-OH

    Fas C- Terminal Tripeptide Chemical Structure
  49. GC46146 FD-211

    (–)-Waol A

     A δ lactone with anticancer activity FD-211 Chemical Structure
  50. GC49563 Fenhexamid

    KBR 2738

     Le fenhexamide, un botryticide, est un inhibiteur de la biosynthèse des stérols. Fenhexamid Chemical Structure
  51. GP10146 ferritin heavy chain fragment [Multiple species]

    H2N-Tyr-Leu-Asn-Glu-Gln-Val-Lys-Ala-Ile-OH

    ferritin heavy chain fragment [Multiple species] Chemical Structure
  52. GC47361 Fludioxonil

    CGA 173506

     A fungicide Fludioxonil Chemical Structure
  53. GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase Forphenicine Chemical Structure
  54. GC52014 Forphenicinol

    Forfenimex

     An immunomodulator and a derivative of forphenicine Forphenicinol Chemical Structure
  55. GC49089 FR900359

    UBO-QIC

    A cyclic depsipeptide and an inhibitor of Gαq, Gα11, and Gα14

     FR900359 Chemical Structure
  56. GC16236 Fucoidan

    Fucan,Sulfated α-L-Fucan

     Le fucoÏdane, un polysaccharide biologiquement actif, est un inhibiteur efficace de l'α-amylase et de l'α-glucosidase. Fucoidan Chemical Structure
  57. GC52483 Fucosylated Ganglioside GM1 (porcine) (ammonium salt)

    Fucosylated Monosialoganglioside GM1, Fucosyl GM1

     A sphingolipid Fucosylated Ganglioside GM1 (porcine) (ammonium salt) Chemical Structure
  58. GC47377 Fumitremorgin B

    Lanosulin

     La fumitrémorgine B est une mycotoxine tremorgénique. Fumitremorgin B Chemical Structure
  59. GC52288 Fumonisin B1-13C34

    FB1-13C34

     An internal standard for the quantification of fumonisin B1 Fumonisin B1-13C34 Chemical Structure
  60. GC47378 Fumonisin B2-13C34

    FB2

     An internal standard for the quantification of fumonisin B2 Fumonisin B2-13C34 Chemical Structure
  61. GC52047 Fustin

    Dihydrofisetin, NSC 59264

     Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) est un puissant inhibiteur de l'amyloÏde β (Aβ). Fustin Chemical Structure
  62. GP10092 G protein coupled receptor [Homo sapiens]

    H2N-Gln-Glu-Ser-His-Asn-Ser-Gly-Asn-Arg-Ser-Asp-Gly-Pro-Gly-Lys-Asn-Thr-Thr-Leu-His-Asn-Glu-Phe-Asp-Thr-OH

    G protein coupled receptor [Homo sapiens], (C110H168N38O45), a peptide with the sequence H2N-QESHNSGNRSDGPGKNTTLHNEFDT-OH, MW= 2742.74. G protein coupled receptor [Homo sapiens] Chemical Structure
  63. GC49420 Gallic Acid-d2

    3,4,5-Trihydroxybenzoic Acid-d2

     An internal standard for the quantification of gallic acid Gallic Acid-d2 Chemical Structure
  64. GC43727 Ganglioside GD1a mixture (sodium salt)

    Ganglioside B1

    Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.

     Ganglioside GD1a mixture (sodium salt) Chemical Structure
  65. GC43728 Ganglioside GD1b Mixture (sodium salt)

    Disialoganglioside GD1b, Ganglioside C1, Ganglioside G2

     Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. Ganglioside GD1b Mixture (sodium salt) Chemical Structure
  66. GC49490 Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt)

    Disialoganglioside GD2 Mixture, Ganglioside GD2, Disialo Mixture

     A semi-synthetic mixture of ganglioside GD2 Ganglioside GD2 Mixture (bovine buttermilk) (ammonium salt) Chemical Structure
  67. GC52505 Ganglioside GT1b (bovine) (sodium salt)

    Ganglioside G1, Trisialoganglioside GT1b

     A sphingolipid Ganglioside GT1b (bovine) (sodium salt) Chemical Structure
  68. GC43735 Ganglioside GT1b Mixture (sodium salt)

    Ganglioside G1 Mixture

    Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit.

     Ganglioside GT1b Mixture (sodium salt) Chemical Structure
  69. GC49229 Ganodermanontriol Le ganodermanontriol, un stérol isolé de Ganoderma lucidum, induit une activité anti-inflammatoire dans les cellules hépatiques endommagées par l'hydroperoxyde de tert-butyle (t-BHP) par l'expression de HO-1. Le ganodermanontriol présente une activité hépatoprotectrice. Ganodermanontriol Chemical Structure
  70. GP10107 Gap 26

    Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg

    Gap 26 Chemical Structure
  71. GP10119 Gap 27

    Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile

    A connexin-mimetic peptide

     Gap 27 Chemical Structure
  72. GC43747 Geranylgeranyl Pyrophosphate (ammonium salt)

    GGPP

    Le pyrophosphate de géranylegéranyle est un intermédiaire dans la voie de la HMG-CoA réductase dérivé directement du pyrophosphate de farnésyle et utilisé dans la biosynthèse des terpènes et des terpénoïdes.

     Geranylgeranyl Pyrophosphate (ammonium salt) Chemical Structure
  73. GC48763 Gestodene-d6

    SHB 331-d6; WL 70-d6

     An internal standard for the quantification of gestodene Gestodene-d6 Chemical Structure
  74. GC18840 Gilvocarcin V

    Anandimycin A, Antibiotic 1072B, DC38V, NSC 338943, NSC 348115, Toromycin A

     Gilvocarcin V is an antitumor antibiotic with a coumarin-based aromatic structure that was orignally isolated from the culture broth of S. Gilvocarcin V Chemical Structure
  75. GC45811 GKK1032B GKK1032B est un composé alcaloÏde présent dans le champignon endophyte Penicillium sp. GKK1032B peut induire l'apoptose des cellules d'ostéosarcome humain MG63 par l'activation de la voie de la caspase. GKK1032B Chemical Structure
  76. GC40049 Glucocorticoid Resistance Inhibitor Glucocorticoid resistance inhibitor is an inhibitor of glucocorticoid resistance. Glucocorticoid Resistance Inhibitor Chemical Structure
  77. GC48720 Griseofulvic Acid

    (±)-Griseofulvic Acid

     A metabolite of griseofulvin Griseofulvic Acid Chemical Structure
  78. GC43784 GRP (human) (trifluoroacetate salt)

    Gastrin-Releasing Peptide (1-27) (human)

     Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. GRP (human) (trifluoroacetate salt) Chemical Structure
  79. GP10115 GTP-Binding Protein Fragment, G alpha

    H2N-Cys-Gly-Ala-Gly-Glu-Ser-Gly-Lys-Ser-Thr-Ile-Val-Lys-Gln-Met-Lys-OH

    GTP-Binding Protein Fragment, G alpha Chemical Structure
  80. GC49048 Guanylin (human) (trifluoroacetate salt) A peptide hormone activator of GC-C Guanylin (human) (trifluoroacetate salt) Chemical Structure
  81. GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. Halofuginone (hydrochloride) Chemical Structure
  82. GC49855 Harmalol (hydrochloride hydrate)

    11-hydroxy Harmalan, Harmidol

     A β-carboline alkaloid and an active metabolite of harmaline Harmalol (hydrochloride hydrate) Chemical Structure
  83. GC40724 Heat Shock Protein Inhibitor II

    Hsp Inhibitor II, KNK 423

     Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Heat Shock Protein Inhibitor II Chemical Structure
  84. GC48388 Heliquinomycin

    NSC 702208, Rubymycin

     A bacterial metabolite with diverse biological activities Heliquinomycin Chemical Structure
  85. GC49882 Hemokinin 1 (human) (trifluoroacetate salt)

    HK-1, TGKASQFFGLM-NH2, Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2

     A peptide agonist of NK1 receptors Hemokinin 1 (human) (trifluoroacetate salt) Chemical Structure
  86. GC49915 Hexa-D-Arginine (trifluoroacetate salt)

    Furin Inhibitor II, Hexa-D-Arg-NH2, Hexa-D-Arginine amide, D6R-NH2, (D)RRRRRR-NH2

     A furin inhibitor Hexa-D-Arginine (trifluoroacetate salt) Chemical Structure
  87. GP10020 Histone-H2A-(107-122)-Ac-OH

    Ac-Gly-Val-Leu-Pro-Asn-Ile-Gln-Ala-Val-Leu-Leu-Pro-Lys-Lys-Thr-Glu-OH

    Histone-H2A peptide

     Histone-H2A-(107-122)-Ac-OH Chemical Structure
  88. GC43866 Histrelin (acetate)

    Des-Gly10,D-His(Bzl)6-LHRHethyl amide, Des-Gly10,D-His(Bzl)6,Pro-NHEt9-LHRH, (ImBzl)-d-His6,Pro9-NET-LHRH

     Histrelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that binds to the GNRH receptor (GNRHR; Ki = 0.2 nM in CHO cells expressing the human receptor). Histrelin (acetate) Chemical Structure
  89. GC52504 Human Vitamin D Receptor Reporter Assay System

    NR1I1, VDR

     A nuclear receptor cell-based reporter assay Human Vitamin D Receptor Reporter Assay System Chemical Structure
  90. GC49282 Hydroxy Lenalidomide

    5-hydroxy Lenalidomide

     A metabolite of lenalidomide Hydroxy Lenalidomide Chemical Structure
  91. GC45959 IKD-8344 A macrocyclic dilactone with diverse biological activities IKD-8344 Chemical Structure
  92. GC49359 IM-156 (acetate)

    HL156A, HL271

     A mitochondrial complex I inhibitor and an AMPKα activator IM-156 (acetate) Chemical Structure
  93. GC52190 Imidazole Ketone Erastin

    IKE

     Imidazole Ketone Erastin est un inhibiteur efficace et métaboliquement stable du système xc- ainsi qu'un inducteur de la ferroptose. Imidazole Ketone Erastin Chemical Structure
  94. GC47454 IMS 2186 An anti-choroidal neovascularization agent IMS 2186 Chemical Structure
  95. GC52472 Inostamycin A (sodium salt)

    Inostamycin

     A bacterial metabolite with anticancer activity Inostamycin A (sodium salt) Chemical Structure
  96. GP10041 Insulin like growth factor II fragment variant

    H2N-Thr-Pro-Thr-Lys-Ser-Glu-Arg-OH

    Insulin like growth factor II fragment variant has a sequence of Thr-Pro-Thr-Lys-Ser-Glu-Arg. Insulin like growth factor II fragment variant Chemical Structure
  97. GC48396 IR 780 IR 780 est une sonde fluorescente heptacyanine utilisée pour l'imagerie in vivo des cellules tumorales, avec un large spectre d'absorption de 750 à 830 nm. IR 780 Chemical Structure
  98. GC48378 IR 783 A fluorescent probe for in vivo tumor cell imaging IR 783 Chemical Structure
  99. GC49634 Isoflupredone

    Δ-Fluorocortisone, 9α-Fluoroprednisolone, NSC 12174

     L'isofluprédone appartient À la classe des corticostéroÏdes et exerce son effet en se liant aux récepteurs glucocorticoÏdes et minéralocorticoÏdes des animaux, tels que les chevaux. Isoflupredone Chemical Structure
  100. GC43920 Isoquinoline-3-carboxylic Acid

    3-Carboxyisoquinoline, 3-Isoquinaldic Acid, NSC 53385

     Isoquinoline-3-carboxylic acid is a synthetic intermediate that has been used to design novel antitumor compounds. Isoquinoline-3-carboxylic Acid Chemical Structure
  101. GC46163 IT-143B A bacterial metabolite IT-143B Chemical Structure

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