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Home >> Signaling Pathways >> Cancer Biology

Cancer Biology

Products for  Cancer Biology

  1. Cat.No. Product Name Information
  2. GC47054 CAY10748 A STING agonist CAY10748 Chemical Structure
  3. GC47064 CAY10770 An inhibitor of CYP4Z1 CAY10770 Chemical Structure
  4. GC47066 CAY10777 An antiproliferative agent CAY10777 Chemical Structure
  5. GC91432 CAY10799

    Di-tert-butyl (((S)-1-(tert-butoxy)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)carbamoyl)-L-glutamate

     CAY10799 is a precursor in the synthesis of prostate-specific membrane antigen (PSMA) ligands and fluorescent probes that have been used in the detection of PSMA in LNCaP and PC3 cells. CAY10799 Chemical Structure
  6. GC43207 Caylin-1 Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-1 Chemical Structure
  7. GC43208 Caylin-2 Nutlin-3 is an activator of p53 that functions by inhibiting the interaction of p53 with MDM2, a negative regulator of p53 activity. Caylin-2 Chemical Structure
  8. GC49664 CB-1158

    INCB 01158, Numidargistat

     An arginase inhibitor CB-1158 Chemical Structure
  9. GP10098 Cdk2/Cyclin Inhibitory Peptide I

    H2N-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Pro-Val-Lys-Arg-Arg-Leu-Phe-Gly-OH

    Cdk2/Cyclin Inhibitory Peptide I Chemical Structure
  10. GC16722 CE3F4 Uncompetitive Epac1 inhibitor CE3F4 Chemical Structure
  11. GC65347 Ceanothic acid Ceanothic acid (Emmolic acid) is a ring-A homologue of betulinic acid. Ceanothic acid inhibits OVCAR-3, HeLa, and FS-5 cells with the cell survival of 68%, 65%, and 81%, respectively. Ceanothic acid Chemical Structure
  12. GC45716 Cerevisterol A fungal metabolite Cerevisterol Chemical Structure
  13. GC43244 Chlorin e6

    Ce6

     Chlorin e6(Ce6) is a second-generation photosensitizer. Chlorin e6 Chemical Structure
  14. GC91297 Cholesterol-Doxorubicin

    A prodrug form of doxorubicin

     Cholesterol-Doxorubicin Chemical Structure
  15. GC43258 Cholesteryl Hemisuccinate

    Cholesteryl hydrogen succinate

     Cholesteryl Hemisuccinate is an acidic cholesterol ester with hepatoprotective and anticancer activities. Cholesteryl Hemisuccinate Chemical Structure
  16. GC18290 Chrysomycin A

    Albacarcin V, NSC 613946, Virenomycin V

     Chrysomycin A is an antibiotic isolated from a strain of Streptomyces. Chrysomycin A Chemical Structure
  17. GC12948 CID-1067700

    ML-282

    competitive inhibitor of nucleotide binding by Ras-related GTPases

     CID-1067700 Chemical Structure
  18. GC41578 cis-10-Heptadecenoic Acid

    (Z)-Heptadec-10-enoic acid

    cis-10-Heptadecenoic acid is a C17:1 monounsaturated fatty acid that is a minor constituent of ruminant fats.

     cis-10-Heptadecenoic Acid Chemical Structure
  19. GC41587 cis-Vaccenic Acid

    C18:1 n-7, C18:1(11Z), cis-11-Octadecenoic Acid

     An ω-7 fatty acid cis-Vaccenic Acid Chemical Structure
  20. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide

    Biotin-GQGKS(Cit)L(Cit)DLYEEEMRELRRQ, Biotin-GQGKSXLXDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (G146R) (R144 + R146)-biotin

     A biotinylated and citrullinated mutant vimentin peptide Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide Chemical Structure
  21. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide

    Biotin-GQGKS(Cit)LGDLYEEEMRELRRQ, Biotin-GQGKSXLGDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (R144)-biotin

     A biotinylated and citrullinated vimentin peptide Citrullinated Vimentin (R144) (139-159)-biotin Peptide Chemical Structure
  22. GC47109 Clotrimazole-d5 An internal standard for the quantification of clotrimazole Clotrimazole-d5 Chemical Structure
  23. GC47117 Colchicine-d6

    An internal standard for the quantification of colchicine

     Colchicine-d6 Chemical Structure
  24. GC43299 Collismycin A

    SF 2738A

     Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. Collismycin A Chemical Structure
  25. GC52018 COTC

    2-Crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone

     A bacterial metabolite with anticancer activity COTC Chemical Structure
  26. GC49569 CP 226,269 A dopamine D4 receptor agonist CP 226,269 Chemical Structure
  27. GC49059 CP94

    CGP 46700, 1,2-Diethyl-3-hydroxypyridin-4-one, EL1Net, 1,2-diethyl HP

     An iron chelator CP94 Chemical Structure
  28. GC62215 CRT0273750 CRT0273750 is an autotaxin (ATX) inhibitor and modulates LPA levels in plasm (IC50 = 0.014 μM). CRT0273750 can be used in ATX/LPA-dependent models of cancer. CRT0273750 Chemical Structure
  29. GC49557 Cu-GTSM

    CuII(gtsm), copper-GTSM

     A copper-containing compound with diverse biological activities Cu-GTSM Chemical Structure
  30. GC47137 Cy5-SE (triethylamine salt)

    Sulfo-Cy5

     An amine-reactive fluorescent probe Cy5-SE (triethylamine salt) Chemical Structure
  31. GP10048 Cyclin D1

    H2N-Leu-Leu-Gly-Ala-Thr-Cys-Met-Phe-Val-OH

    G1/S-specific cyclin-D1 (H2N-Leu-Leu-Gly-Ala-Thr-Cys-Met-Phe-Val-OH) is a protein that in humans is encoded by the CCND1 gene. Cyclin D1 Chemical Structure
  32. GP10038 Cyclin dependent kinase inhibitor 2A - Tumor Suppressor

    H2N-Met-Val-Arg-Arg-Phe-Leu-Val-Thr-Leu-Arg-Ile-Arg-Arg-Ala-Cys-Gly-Pro-Pro-Arg-Val-OH

    Cyclin dependent kinase inhibitor 2A (CDKN2A, p16Ink4A) (H2N-Met-Val-Arg-Arg-Phe-Leu-Val-Thr-Leu-Arg-Ile-Arg-Arg-Ala-Cys-Gly-Pro-Pro-Arg-Val-OH), also known as multiple tumor suppressor 1 (MTS-1), is a tumor suppressor protein, which in humans is encoded by the CDKN2A gene.

     Cyclin dependent kinase inhibitor 2A - Tumor Suppressor Chemical Structure
  33. GC43342 Cyclo(L-Leu-L-Pro)

    Maculosin 6

     Cyclo(L-Leu-L-Pro) is a diketopiperazine metabolite that has been isolated from various bacterial and fungal species including Streptomyces. Cyclo(L-Leu-L-Pro) Chemical Structure
  34. GC49707 Cyclo(RGDfC) (trifluoroacetate salt)

    c(RGDfC), cyclo(Arg-Gly-Asp-D-Phe-Cys)

     A cyclic pentapeptide Cyclo(RGDfC) (trifluoroacetate salt) Chemical Structure
  35. GC49709 cyclo(RGDyC) (trifluoroacetate salt)

    c(RGDyC), cyclo(Arg-Gly-Asp-D-Tyr-Cys)

     A cyclic pentapeptide cyclo(RGDyC) (trifluoroacetate salt) Chemical Structure
  36. GP10143 Cytochrome c - pigeon (88-104)

    H2N-Lys-Ala-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Ala-Lys-OH

    Cytochrome c - pigeon (88-104) Chemical Structure
  37. GP10007 Cytochrome c fragment (93-108)

    H2N-Ala-Asn-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Lys-OH

    Initiates apoptosis

     Cytochrome c fragment (93-108) Chemical Structure
  38. GP10141 Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]

    H2N-Phe-Leu-Asp-Pro-Arg-Pro-Leu-Thr-Val-OH

    Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] Chemical Structure
  39. GC43361 Cytostatin (sodium salt) Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. Cytostatin (sodium salt) Chemical Structure
  40. GC91419 CYY292 CYY292 is an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, (IC50s = 5.35, 4.6, 28, 28, and 78 nM, respectively). CYY292 Chemical Structure
  41. GC43368 D,L-1′-Acetoxychavicol Acetate

    ACA, 1'-Acetoxychavicol Acetate, Galangal Acetate

     D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. D,L-1′-Acetoxychavicol Acetate Chemical Structure
  42. GC43504 D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt)

    IP6, Phytic Acid

     Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt) Chemical Structure
  43. GC47168 Daidzein-d4 An internal standard for the quantification of daidzein Daidzein-d4 Chemical Structure
  44. GC60121 Dasatinib D8

    Sprycel-d8

     An internal standard for the quantification of GC- or LC-MS Dasatinib D8 Chemical Structure
  45. GC48581 Daunorubicinone

    (+)-Daunomycinone, NSC 109531

     An aglycone form of daunorubicin Daunorubicinone Chemical Structure
  46. GC40697 DDA

    Decadienealdehyde, trans2,4Decadien1al

     DDA is a lipid peroxidation product of linolieic acid. DDA Chemical Structure
  47. GC43390 Deacetylravidomycin Deacetylravidomycin is a microbial metabolite that has been found in Streptomyces and has light-dependent antibiotic and anticancer activities. Deacetylravidomycin Chemical Structure
  48. GC43391 Decanoic Acid (sodium salt)

    C10:0, Capric Acid, Decylic Acid

     Decanoic acid is a saturated medium-chain fatty acid that contains 10 carbons. Decanoic Acid (sodium salt) Chemical Structure
  49. GC45815 Decanoic Acid-d19

    Capric Acid-d19, Decylic Acid-d19

     An internal standard for the quantification of decanoic acid Decanoic Acid-d19 Chemical Structure
  50. GC46127 Decanoic Acid-d2

    C10:0-d2, Capric Acid-d2, Decylic Acid-d2

     An internal standard for the quantification of decanoic acid Decanoic Acid-d2 Chemical Structure
  51. GC45722 Decanoic Acid-d3

    Capric Acid-d3, Decylic Acid-d3

     An internal standard for the quantification of decanoic acid Decanoic Acid-d3 Chemical Structure
  52. GC40230 Deferasirox-d4 Deferasirox-d4 is intended for use as an internal standard for the quantification of deferasirox by GC- or LC-MS. Deferasirox-d4 Chemical Structure
  53. GC52316 Deferitrin

    GT-56-252, (S)-4'-Hydroxydesazadesferrithiocin

     An iron chelator and derivative of desferrithiocin Deferitrin Chemical Structure
  54. GC43407 Demethylwedelolactone Demethylwedelolactone (DWL) is a coumestan, originally isolated from E. Demethylwedelolactone Chemical Structure
  55. GC40654 Deoxyviolacein Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein that has anticancer, antibacterial, and antifungal properties. Deoxyviolacein Chemical Structure
  56. GC47211 Dichlorvos

    DDVP, Dichlorovinyl Dimethyl Phosphate, NSC 6738

     An organophosphate insecticide Dichlorvos Chemical Structure
  57. GC49293 Dichlorvos-d6

    DDVP-d6, Dichlorovinyl Dimethyl Phosphate-d6

     An internal standard for the quantification of dichlorvos Dichlorvos-d6 Chemical Structure
  58. GC47215 Dienogest-d8 An internal standard for the quantification of dienogest Dienogest-d8 Chemical Structure
  59. GC52194 Dimethylamino Parthenolide

    DMAPT, LC-1

     Dimethylamino Parthenolide Chemical Structure
  60. GC74493 Dinutuximab

    Unituxin; APN-311

     Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab Chemical Structure
  61. GC49383 DL-Phenyl-d5-alanine

    (±)-Phenyl-d5-alanine

     An internal standard for the quantification of DL-phenylalanine DL-Phenyl-d5-alanine Chemical Structure
  62. GC18254 DM1-SMe DM1-SMe is an analog of mertansine with a thiomethane cap attached to the sulfhydryl group. DM1-SMe Chemical Structure
  63. GC48968 Docetaxel (hydrate)

    DTX, NSC 628503, RP 56976, Taxotel

    An analog of taxol with antitumor properties

     Docetaxel (hydrate) Chemical Structure
  64. GC47250 Docetaxel-d9

    DTX-d9, Taxotel-d9

    An internal standard for the quantification of docetaxel

     Docetaxel-d9 Chemical Structure
  65. GC74603 Domvanalimab

    AB154

     Domvanalimab (AB154) is an anti-TIGIT humanized monoclonal antibody. Domvanalimab Chemical Structure
  66. GC43565 Doxorubicinol (hydrochloride)

    13-Dihydroadriamycin hydrochloride

     Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. Doxorubicinol (hydrochloride) Chemical Structure
  67. GC40082 Drimentine B Drimentine B is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. Drimentine B Chemical Structure
  68. GC43573 Drimentine C Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. Drimentine C Chemical Structure
  69. GC49001 DSPE-PEG(2000)-amine (sodium salt) A PEGylated derivative of DSPE DSPE-PEG(2000)-amine (sodium salt) Chemical Structure
  70. GC91884 DSPE-PEG(2000)-Mannose

    1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-Mannose; 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-Polyethylene Glycol-2000-Mannose; 1,2-DSPE-PEG(2000)-Mannose

     DSPE-PEG(2000)-mannose has been used in the generation of liposomes and mixed micelles for the delivery of anticancer agents to tumor-associated macrophages (TAMs) in vitro and in vivo. DSPE-PEG(2000)-Mannose Chemical Structure
  71. GC52333 DSPE-PEG(2000)-NHS

    DSPE-PEG(2000)-NHS is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE .

     DSPE-PEG(2000)-NHS Chemical Structure
  72. GC26427 DSPE-PEG2000-Mal ammonium

    Poly(oxy-1,2-ethanediyl), α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]-, ammonium salt (1:1)

     DSPE-PEG2000-Mal ammonium Chemical Structure
  73. GC49058 DTPA

    Diethylenetriaminepentaacetic Acid, NSC 7340, Pentetic Acid

     DTPA is a compound used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. DTPA Chemical Structure
  74. GC18992 Duclauxin

    NSC 258308

     Duclauxin decreases proliferation of tumor cells in vitro and increases the lifespan of mice innoculated with Ehrlich ascitic tumor cells. Duclauxin Chemical Structure
  75. GP10022 Dynamin inhibitory peptide

    Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro

    Dynamin inhibitory peptide Chemical Structure
  76. GC65123 Eclalbasaponin I Eclalbasaponin I is isolated from Eclipta prostrata L with antitumor activity. Eclalbasaponin I inhibits the proliferation of hepatoma cell smmc-7721 with an IC50 value of 111.1703 μg/ml. Eclalbasaponin I Chemical Structure
  77. GP10030 EGF receptor substrate eps15 acetyl - [Mus musculus]/[Homo sapiens]

    Ac-Gln-Glu-Gln-Glu-Asp-Leu-Glu-Leu-Ala-Ile-Ala-Leu-Ser-Lys-Ser-Glu-Ile-Ser-Glu-Ala-OH

    EGF receptor substrate eps15 (Eps15) has been identified as a 142-kDa substrate of the EGF receptor1. EGF receptor substrate eps15 acetyl - [Mus musculus]/[Homo sapiens] Chemical Structure
  78. GP10108 EGF-R (661-681) T669 Peptide

    H2N-Lys-Arg-Glu-Leu-Val-Glu-Pro-Leu-Thr-Pro-Ser-Gly-Glu-Ala-Pro-Asn-Gln-Ala-Leu-Leu-Arg-OH

    EGF-R (661-681) T669 Peptide Chemical Structure
  79. GC43591 Eicosapentaenoyl 1-propanol-2-amide Monoacylglycerols (MAGs) of ω-3 polyunsaturated fatty acids have diverse physiological and health effects. Eicosapentaenoyl 1-propanol-2-amide Chemical Structure
  80. GC49522 EM-12

    EM-12

     EM-12 (EM-12), a teratogenic Thalidomide analogue, is more active than Thalidomide and is much more stable for hydrolysis. EM-12 enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas. EM-12 Chemical Structure
  81. GC46137 Emestrin A mycotoxin Emestrin Chemical Structure
  82. GC49124 EN219 EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination. EN219 Chemical Structure
  83. GP10117 Endostatin (84-114)-NH2 (JKC367)

    H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2

    Endostatin (84-114)-NH2 (JKC367) Chemical Structure
  84. GC43606 Endothelin-1 (human, porcine) (trifluoroacetate salt)

    ET-1

     Endothelin-1 is a peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively). Endothelin-1 (human, porcine) (trifluoroacetate salt) Chemical Structure
  85. GC49648 Enobosarm-d4

    (S)-Enobosarm-d4

     An internal standard for the quantification of enobosarm Enobosarm-d4 Chemical Structure
  86. GC48664 Enoxacin-d8 (hydrochloride) Enoxacin-d8 (hydrochloride) Chemical Structure
  87. GC47297 EP4 Receptor Antagonist 1 An EP4 receptor antagonist EP4 Receptor Antagonist 1 Chemical Structure
  88. GP10005 Epidermal growth factor receptor (994-1002) acetyl/amide

    Ac-Asp-Ser-Asn-Phe-Tyr-Arg-Ala-Leu-Met-amide

    EGF-family receptor

     Epidermal growth factor receptor (994-1002) acetyl/amide Chemical Structure
  89. GP10095 Epidermal Growth Factor Receptor Peptide (985-996)

    H2N-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH

    Epidermal Growth Factor Receptor Peptide (985-996) Chemical Structure
  90. GC72845 Epoetin beta

    rhEPO; EPOCH; Genetical recombination

     Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta Chemical Structure
  91. GP10132 erbB-2

    H2N-Lys-Ile-Phe-Gly-Ser-Leu-Ala-Phe-Leu-OH

    erbB-2 Chemical Structure
  92. GC90653 ERX-41

    An ER stress inducer

     ERX-41 Chemical Structure
  93. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil Ethyl Mycophenolate Chemical Structure
  94. GC74618 Etigilimab

    OMP-313M32

     Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, blocks TIGIT interaction with PVR (CD155; poliovirus receptor) and inhibits downstream signalling with target cell killing. Etigilimab Chemical Structure
  95. GC15555 Farnesyl Thiosalicylic Acid Amide

    FTS Amide,Salirasib Amide

    inhibits tumor growth

     Farnesyl Thiosalicylic Acid Amide Chemical Structure
  96. GP10123 Fas C- Terminal Tripeptide

    Ac-Ser-Leu-Val-OH

    Fas C- Terminal Tripeptide Chemical Structure
  97. GC60833 FB23 FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity. FB23 Chemical Structure
  98. GC46146 FD-211

    (-)-Waol A

     A δ lactone with anticancer activity FD-211 Chemical Structure
  99. GC49563 Fenhexamid

    KBR 2738

     Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid Chemical Structure
  100. GP10146 ferritin heavy chain fragment [Multiple species]

    H2N-Tyr-Leu-Asn-Glu-Gln-Val-Lys-Ala-Ile-OH

    ferritin heavy chain fragment [Multiple species] Chemical Structure
  101. GC39811 FIT-039 FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 Chemical Structure

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