Thalidomide-propargyl |
| Catalog No.GC38862 |
Le thalidomide-propargyl est le ligand Cereblon À base de thalidomide utilisé dans le recrutement de la protéine CRBN. Le thalidomide-propargyle peut être connecté au ligand de la protéine par un lieur pour former l'IMiD contenant les PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2098487-39-7
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs[1].
[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
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