UNC0379 |
| Catalog No.GC16741 |
UNC0379 est un inhibiteur sélectif et compétitif du substrat de la lysine méthyltransférase SETD8 (KMT5A) avec une IC50 de 7,3 μM, une valeur KD de 18,3 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1620401-82-2
Sample solution is provided at 25 µL, 10mM.
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UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 μM; selective over 15 other methyltransferases[1].
References:
[1]. Ma A, et al. Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8. J Med Chem. 2014 Aug 14;57(15):6822-33.
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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