19(S)-HETE (Synonyms: 19(S)-Hydroxyeicosatetraenoic Acid) |
| カタログ番号GC40458 |
19-HETEは、アラキドン酸の主要なシトクロムP450（CYP450）代謝物の1つであり、アンジオテンシンIIに対する腎臓から放出されます。
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Cas No.: 115461-40-0
Sample solution is provided at 25 µL, 10mM.
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19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.
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