2,3-dinor Prostaglandin E1 (Synonyms: 2,3dinor PGE1) |
カタログ番号GC18830 |
プロスタグランジンE1(PGE1)は、自然に存在する主要なプロスタグランジンではありませんが、末梢閉塞性血管疾患、勃起不全および新生児心臓病などのいくつかの適応症で広く臨床的に投与されています。
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Cas No.: 7046-40-4
Sample solution is provided at 25 µL, 10mM.
Prostaglandin E1 (PGE1) is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction and in neonatal cardiology. The metabolism of PGE1 is normally initiated by oxidation at C-15, resulting in 13,14-dihydro-15-keto PGE1 as the major metabolite. However, inhibition of this pathway or saturation by excess substrate could theoretically lead to enhanced production of 2,3-dinor metabolites, including 2,3-dinor PGE1. The biological activity of 2,3-dinor PGE1 has not been published.
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