5-hydroxy-6-methoxy (S)-Duloxetine |
| カタログ番号GC42550 |
5-ヒドロキシ-6-メトキシ（S）-デュロキセチンは、（S）-デュロキセチンの代謝物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 741693-79-8
Sample solution is provided at 25 µL, 10mM.
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5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine . It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S)-Duloxetine binds to the serotonin (5-HT), norepinephrine, and dopamine transporters with Ki values of 266, 920, and 2,814 nM, respectively.
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