8-Bromo-cGMP, sodium salt (Synonyms: 8-bromo-cGMP, 8-bromo Guanosine 3’,5’-cyclic monophosphate) |
| カタログ番号GC10119 |
8-Bromo-cGMP、ナトリウム塩、cGMP の膜透過性類似体は、PKG (プロテインキナーゼ G) 活性化因子です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 51116-01-9
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase.[1] At 1 µM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.[2]
Reference:
[1]. Rashatwar, S.S., Cornwell, T.L., and Lincoln, T.M. Effects of 8-bromo-cGMP on Ca2+ levels in vascular smooth muscle cells: Possible regulation of Ca2+-ATPase by cGMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America 84(16), 5685-5689 (1987).
[2]. Choi, J., and Farley, J.M. Effects of 8-bromo-cyclic GMP on membrane potential of single swine tracheal smooth muscle cells. Journal of Pharmacology and Experimental Therapeutics 285(2), 588-594 (1998).
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *