9(E),11(E),13(E)-Octadecatrienoic Acid (Synonyms: β-Eleostearic Acid, β-ESA) |
カタログ番号GC41642 |
9(E),11(E),13(E)-オクタデカトリエン酸(β-ESA)は、植物の種子油やリノレン酸のアルカリ異性化によって合成された共役リノール酸混合物中に存在する共役多価不飽和脂肪酸です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 544-73-0
Sample solution is provided at 25 µL, 10mM.
9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner. In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces apoptosis in T24 bladder cancer cells via production of reactive oxygen species. It also inhibits bacterial fatty acid dioxygenase with a Ki value of 49 nM in vitro.
Average Rating: 5
(Based on Reviews and 32 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *