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AM-4668

カタログ番号GC34464

AM-4668 は、2 型糖尿病に対する GPR40 アゴニストです。

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AM-4668 化学構造

Cas No.: 1011531-27-3

サイズ 価格 在庫数
5mg
$260.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1]. EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)[1]

[1]. Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5(5):517-21.

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