AM-4668 |
カタログ番号GC34464 |
AM-4668 は、2 型糖尿病に対する GPR40 アゴニストです。
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Cas No.: 1011531-27-3
Sample solution is provided at 25 µL, 10mM.
AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1]. EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)[1]
[1]. Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5(5):517-21.
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