AVE5688 |
| カタログ番号GC31627 |
AVE5688 はグリコーゲンホスホリラーゼ (GP) の阻害剤であり、IC50 は 430 nM と 915 nM、Kds はウサギ筋グリコーゲンホスホリラーゼ (それぞれ rmGPb と rmGPa) に対して 170 nM と 530 nM です。 AVE5688 は 2 型糖尿病の研究に使用できます。
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Cas No.: 613260-13-2
Sample solution is provided at 25 µL, 10mM.
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AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively)[1].
[1]. Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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