AVE5688 |
| Katalog-Nr.GC31627 |
AVE5688 ist ein Inhibitor der Glykogenphosphorylase (GP) mit IC50-Werten von 430 nM und 915 nM und Kds von 170 nM und 530 nM fÜr Kaninchenmuskel-Glykogenphosphorylase (rmGPb bzw. rmGPa); AVE5688 kann zur Erforschung von Typ-2-Diabetes eingesetzt werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 613260-13-2
Sample solution is provided at 25 µL, 10mM.
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AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively)[1].
[1]. Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91.
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