AZD-5069 |
| カタログ番号GC32707 |
AZD-5069 は、がん治療に使用される強力な CXCR2 ケモカイン受容体拮抗薬です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 878385-84-3
Sample solution is provided at 25 µL, 10mM.
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AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.
AZD-5069 (Compound 2) acts as CXCR2 antagonist by inhibition of [125I]-IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye[1].
[1]. Norman P. Evidence on the identity of the CXCR2 antagonist AZD-5069. Expert Opin Ther Pat. 2013 Jan;23(1):113-7.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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