GW9662
GW9662 exhibits half maximal inhibitory concentration (IC50) of 3.3 nM and is a well-characterized inhibitor of peroxisome proliferator-activated receptor gamma (PPARγ), demonstrating high selectivity for PPARy with the inhibitory activity greater for PPARγ about 10 to 600 times compared to PPARα and PPARδ in cellular environments.
Deferoxamine Mesylate
In the vast expanse of medical science, where each discovery is a step towards unraveling the mysteries of human health, Deferoxamine Mesylate emerges as a pivotal breakthrough in the realm of iron chelation therapy.
Brefeldin A
Cytotoxin Produced by diverse kinds of fungi e.g Paecilomyces sp. And Aspergillus clavatus isolated from Taxus mairei and Torreya grandis from Southeast china, 12,15-Dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one also called as Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor.
Mdivi 1
Mitochondrial division inhibitor-1 (Mdivi-1) ( mol.weight : 353.22, empirical formula: C15H10Cl2N2O2S) is a small chemical inhibitor of mitochondrial division dynamin, which plays multiple roles in mitochondrial dynamics, mitochondrial autophagy, ATP production, the immune response, and Ca²⁺ homeostasis.
RIPA Lysis Buffer (Strong)
RIPA Lysis Buffer is a traditional rapid lysis buffer for cellular tissues. It is a lysis and washing buffer that is used in reporter gene detection, protein kinase experiments, immunoassays, and protein purification.
BODIPY 493/503
BODIPY 493/503 (4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-SIndacene) usually employed for the quantification of neutral lipid content by utilizing flow cytometry and for the observation of lipid droplets by microscopy, is a fluorescent and a neutral lipid.
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