Antidepressant agent 1 |
| カタログ番号GC60050 |
抗うつ剤１は、抗うつ作用を有するピラジドール－ハロゲノ誘導体である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 67411-41-0
Sample solution is provided at 25 µL, 10mM.
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Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. Antidepressant agent 1 also can be used to increase body temperature[1].
Antidepressant agent 1 (compound I) is prepared in 56% yields by reduction of compound II by NaBH4-AcOH. Compound II is obtained by condensation of compound III with BrCH2CH(OBu)2 followed by acid-catalyzed cyclization[1].
[1]. V. I. Shvedov, et al. Synthesis and properties of new analogs of pyrazidole-halogeno-derivatives of 1,10-trimethylene-2-ethyl-1,2,3,4-tetrahydropyrazino [1,2-a]indole. Pharmaceutical Chemistry Journal volume 12, pages633-635(1978).
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