SWE101 |
| カタログ番号GC61309 |
ＳＷＥ１０１（化合物２２ｂ）は、強力な可溶性エポキシド加水分解酵素（ｓＥＨ）－Ｐ阻害剤であり、ヒトおよびラットのｓＥＨ－Ｐに対してそれぞれ４μＭおよび２．８μＭのＩＣ５０を有する。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2376322-12-0
Sample solution is provided at 25 µL, 10mM.
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SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH[1].
[1]. Kramer JS, et al. Discovery of first in vivo active inhibitors of soluble epoxide hydrolase (sEH) phosphatase domain. J Med Chem. 2019 Aug 22.
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