m-Methoxybenzamide (Synonyms: m-Anisamide, meta-Methoxybenzamide, NSC 28589, NSC 209527) |
カタログ番号GC47693 |
ADP-リボシルトランスフェラーゼ (ADPRT) および PARP の阻害剤である m-メトキシベンズアミド (3-MBA) は、枯草菌の細胞分裂を阻害し、細胞のフィラメント化と最終的な溶解を引き起こします。 m-メトキシベンズアミド (3-MBA) は、青ジャガイモ (Solanum tuberosum L. subsp. andigenum) の in vitro での植物成長、微小塊形成、および形質転換効率を高めます。
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Cas No.: 5813-86-5
Sample solution is provided at 25 µL, 10mM.
m-Methoxybenzamide is an inhibitor of poly(ADP-ribose) polymerase (PARP; Ki = <2 µM).1 It also inhibits human placental ADP ribosyl transferase activity by 93% when used at a concentration of 100 µM.2 m-Methoxybenzamide (100, 200, and 300 mg/kg) increases the pain threshold in the paw pinch test in rats.3
1.Purnell, M.R., and Whish, W.J.Novel inhibitors of poly(ADP-ribose) synthetaseBiochem. J.185(3)775-777(1980) 2.Burtscher, H.J., Auer, B., Klocker, H., et al.Isolation of ADP-ribosyltransferase by affinity chromatographyAnal. Biochem.152(2)285-290(1986) 3.Sanders, R., Dill, R.E., Dorris, R.L., et al.Analgesic effects of 3-methoxybenzamide in ratsJ. Pharm. Pharmacol.41(4)268-269(1989)
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