m-Methoxybenzamide (Synonyms: m-Anisamide, meta-Methoxybenzamide, NSC 28589, NSC 209527) |
| Katalog-Nr.GC47693 |
m-Methoxybenzamid (3-MBA), ein Inhibitor der ADP-Ribosyltransferase (ADPRTs) und PARP, hemmt die Zellteilung in Bacillus subtilis, was zur Filamentation und schließlich zur Lyse der Zellen fÜhrt. m-Methoxybenzamid (3-MBA) verbessert in vitro das Pflanzenwachstum, die Mikrotuberisierung und die Transformationseffizienz der blauen Kartoffel (Solanum tuberosum L. subsp. andigenum).
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Cas No.: 5813-86-5
Sample solution is provided at 25 µL, 10mM.
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m-Methoxybenzamide is an inhibitor of poly(ADP-ribose) polymerase (PARP; Ki = <2 µM).1 It also inhibits human placental ADP ribosyl transferase activity by 93% when used at a concentration of 100 µM.2 m-Methoxybenzamide (100, 200, and 300 mg/kg) increases the pain threshold in the paw pinch test in rats.3
1.Purnell, M.R., and Whish, W.J.Novel inhibitors of poly(ADP-ribose) synthetaseBiochem. J.185(3)775-777(1980) 2.Burtscher, H.J., Auer, B., Klocker, H., et al.Isolation of ADP-ribosyltransferase by affinity chromatographyAnal. Biochem.152(2)285-290(1986) 3.Sanders, R., Dill, R.E., Dorris, R.L., et al.Analgesic effects of 3-methoxybenzamide in ratsJ. Pharm. Pharmacol.41(4)268-269(1989)
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