Celecoxib Carboxylic Acid |
| カタログ番号GC49152 |
セレコキシブの不活性代謝物
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 170571-01-4
Sample solution is provided at 25 µL, 10mM.
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Celecoxib carboxylic acid is an inactive metabolite of the COX-2 inhibitor celecoxib .1,2 It is formed from celecoxib primarily by the cytochrome P450 (CYP) isoform CYP2C9.
1.Liu, H., Huang, X., Shen, J., et al.Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: Molecular docking and 3D QSAR analysesJ. Med. Chem.45(22)4816-4827(2002) 2.Kim, S.-H., Kim, D.-H., Byeon, J.-Y., et al.Effects of CYP2C9 genetic polymorphisms on the pharmacokinetics of celecoxib and its carboxylic acid metaboliteArch. Pharm. Res.40(3)382-390(2017)
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