3-Aminosalicylic Acid (Synonyms: 3-ASA, NSC 285111) |
| カタログ番号GC49849 |
サリチル酸誘導体
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 570-23-0
Sample solution is provided at 25 µL, 10mM.
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3-Aminosalicylic acid is a salicylic acid derivative and potential impurity in commercial preparations of 5-aminosalicylic acid.1,2 It protects against apoptosis, as well as reverses reductions in mitochondrial complex I, also known as NADH dehydrogenase, activity and increases in reactive oxygen species (ROS) production induced by manganese in SK-N-MC cells when used at a concentration of 1 µM.1
1.Yoon, H., Lee, G.-H., Kim, D.-S., et al.The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronal death: ER stress and mitochondrial complexesToxicol. In Vitro25(7)1259-1268(2011) 2.Gotti, R., Pomponio, R., Bertucci, C., et al.Determination of 5-aminosalicylic acid related impurities by micellar electrokinetic chromatography with an ion-pair reagentJ. Chromatogr. A916(1-2)175-183(2001)
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