VU6012962 |
| カタログ番号GC34320 |
VU6012962 は、347 nM の IC50 を持つ、経口で生物学的に利用可能で、中枢神経系に浸透する代謝型グルタミン酸受容体 7 ネガティブ アロステリック モジュレーター (mGlu7 NAM) です 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2313526-86-0
Sample solution is provided at 25 µL, 10mM.
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VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 (mGlu7) negative allosteric modulator (NAM) with an IC50 of 347 nM[1].
[1]. Reed CW, et al. Discovery of an orally bioavailable and Central Nervous System (CNS) penetrant mGlu7 NegativeAllosteric Modulator (NAM) in vivo tool compound: N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU6012962). J Med Chem. 2019 Jan 4.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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