CG 4305 |
| カタログ番号GC43233 |
プロスタサイクリン（PGI2）は、血管内皮細胞に存在する抗血栓性を持つシクロオキシゲナーゼ代謝物です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells. The half-life is short both in vivo and in vitro, ranging from 30 seconds to a few minutes. CG 4305 is a stable carbacyclic analog of PGI2 that inhibits ADP-induced platelet aggregation 25% at a concentration of 50 nM. Doses of 10 mg/kg (oral) or 1 mg/kg (intraduodenal) have been shown to prevent rabbit carotid artery thrombosis.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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