Oxyntomodulin (bovine, porcine) (trifluoroacetate salt) (Synonyms: Glucagon-37 (bovine, porcine)) |
| カタログ番号GC44524 |
オキシントモドリンは、グルカゴン-37としても知られており、牛や豚の腸で産生される37アミノ酸ペプチドです。
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Sample solution is provided at 25 µL, 10mM.
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Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut. It reduces [125I]-glucagon binding to rat liver plasma membranes and a glucagon antibody in a concentration-dependent manner. Oxyntomodulin induces insulin secretion in a glucose- and concentration-dependent manner in perfused rat pancreas. It increases glucose absorption in isolated rat small intestine and enterocytes. In vivo, oxyntomodulin (25-450 pmol/kg) inhibits pentagastrin-stimulated gastric acid secretion in a dose-dependent manner in rats. It also increases plasma concentrations of insulin and glucose in Holstein cattle under normal physiological conditions.
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