Z-DEVD-CMK (trifluoroacetate salt) (Synonyms: Z-Asp-Glu-Val-Asp-CMK ) |
| カタログ番号GC45178 |
Z-DEVD-CMKはプロテアーゼ阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Z-DEVD-CMK is a protease inhibitor. It irreversibly inhibits recombinant caspase-3, cathepsin B, cathepsin L, cathepsin V, cathepsin F, and cathepsin S in enzyme assays but has no effect on these cathepsins in Jurkat T cells. Z-DEVD-CMK (3 mg/kg) improves endotoxin-induced myocardial dysfunction and reduces caspase-1, -3, and -8 activation and apoptosis in a rat model of endotoxin-induced myocardial dysfunction and heart apoptosis.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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