Cdk2 Inhibitor II (Synonyms: Cyclin-dependent kinase 2 Inhibitor II, SC-221409) |
カタログ番号GC43219 |
サイクリン依存性キナーゼ2(Cdk2)は、細胞周期中のS期およびG2-M移行を調節するためにサイクリンAまたはEと共に機能します。
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Cas No.: 222035-13-4
Sample solution is provided at 25 µL, 10mM.
The cyclin-dependent kinase 2 (Cdk2) works with cyclins A or E to regulate S phase and G2-M transition during the cell cycle. Cdk2 Inhibitor II is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 (IC50 = 60 nM). It is cell permeable, reversible, and ATP-competitive.
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