Cotadutide acetate (Synonyms: MEDI0382 acetate) |
| カタログ番号GC39364 |
コタデュチド（MEDI0382）アセテートは、グルカゴン様ペプチド-1（GLP-1）とGCGRの強力な二重作動薬であり、それぞれEC50値が6.9 pMおよび10.2 pMです。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Cotadutide acetate (MEDI0382 acetate) is a potent peptide dual agonist of glucagon-like peptide-1 (GLP-1) and glucagon receptor with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide acetate (MEDI0382 acetate) exhibits ability to facilitate both weight loss and glycaemic control, has the potential for obesity and type 2 diabetes (T2D) treatment[1].
[1]. Henderson SJ,et al. Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates.Diabetes Obes Metab. 2016 Dec;18(12):1176-1190.
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