Cy7 azide (non-sulfonated) |
カタログ番号GC10791 |
アルキン修飾オリゴヌクレオチドをラベルするために使用されるクリック化学
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Cy7 azide is a labeling reagent that ready for the use in Click Chemistry labeling. This labeling dye is a near-infrared dye which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecules is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. This product can be used for the incorporation of Cy7 azide into various biomolecules and post-synthetic modification of oligonucleotides is also available.
PEG-b-PPLG-Cy7 was conjugated by Cy7 azid and the polymer of PEG-b-PPLG. In blank micelles, it was used to probe the association of unimers [1].
Reference:
[1] Morton, S. W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials,2014, 35(11), 3489-3496.
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