HAEGTFTSDVS |
| カタログ番号GC31416 |
HAEGTFTSDVS は、GLP-1 ペプチドの最初の N 末端の 1 ～ 11 残基です。
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Cas No.: 864915-61-7
Sample solution is provided at 25 µL, 10mM.
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HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2].
[1]. US20120264685 [2]. US9738697
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