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D-3263 hydrochloride

カタログ番号GC32961

D-3263 塩酸塩は、腸溶コーティングされた、経口で生物学的に利用可能な (一過性受容体潜在メラスタチン メンバー 8) TRPM8 アゴニストです。

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D-3263 hydrochloride 化学構造

Cas No.: 1008763-54-9

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$232.00
在庫あり
1mg
$110.00
在庫あり
5mg
$258.00
在庫あり
10mg
$405.00
在庫あり
50mg
$1,195.00
在庫あり
100mg
$1,930.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist.

D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. D-3263 hydrochloride may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH[1].

[1]. enteric-coated TRPM8 agonist D-3263 hydrochloride

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Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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