D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (sodium salt) (Synonyms: IP6, Phytic Acid) |
カタログ番号GC43504
One-Click Copy Product Info
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フィチン酸 (イノシトール六リン酸) 六ナトリウムは、種子や穀物のリン貯蔵化合物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 34367-89-0
Sample solution is provided at 25 µL, 10mM.
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D-myo-Inositol-1,2,3,4,5,6-hexaphosphate (IP6) is a phosphate ester of inositol. It is found in mammalian cells and undergoes interconversion to other forms of inositol phosphate that act as second messengers in cell signaling. IP6 is an antioxidant that chelates iron at a molar ratio of 1:4 to reduce iron-induced hydroxy radical production and lipid peroxidation in cell-free assays. It also inhibits the formation of thiobarbituric acid reacting substances (TBARS) in cooked chicken breast when used at a concentration of 1.5 mM. IP6 inhibits proliferation of a variety of cancer cells in vitro and reduces tumor growth in rodent xenograft models. It is also known as phytic acid and is considered an anti-nutrient that binds minerals, including calcium, iron, magnesium, and zinc, in grains, legumes, oilseeds, nuts, and other plants and prevents their absorption in the gastrointestinal tract of humans and animals that ingest them. Formulations containing phytic acid have been used as preservatives in food production.
| Cas No. | 34367-89-0 | SDF | |
| 同義語 | IP6, Phytic Acid | ||
| Canonical SMILES | O=P(O[C@H]1[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1OP(O)([O-])=O)([O-])O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] | ||
| Formula | C6H12O24P6•6Na | M.Wt | 791.9 |
| 溶解度 | Water: 50 mg/ml | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.2628 mL | 6.3139 mL | 12.6279 mL |
| 5 mM | 252.6 μL | 1.2628 mL | 2.5256 mL |
| 10 mM | 126.3 μL | 631.4 μL | 1.2628 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)