Disopyramide (Synonyms: (±)-Disopyramide, Ritmilen, SC-7031) |
カタログ番号GC43478 |
ジソピラミド(ディコランチル)は、心室および心房性不整脈に有効なクラス IA の抗不整脈薬です。
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Cas No.: 3737/9/5
Sample solution is provided at 25 µL, 10mM.
Disopyramide is a sodium channel blocker that, in rabbit ventricular myocytes, binds and dissociates from open channels more quickly than from resting channels. It is a class Ia antiarrhythmic agent that delays conduction through the AV node and ventricles of the dog heart both in vivo (3 and 5 mg/kg) and in vitro (1-2 mg/L). Formulations containing disopyramide have been used in the treatment of cardiac arrhythmias and hypertrophic cardiomyopathy.
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