EGFR-IN-9 |
| カタログ番号GC65974 |
EGFR-IN-9 (化合物 8) は、野生型 EGFR キナーゼおよび二重変異体 EGFR キナーゼ (L858R/T790M) に対して 7 nM、28 nM の IC50 を持つ強力な EGFR キナーゼ阻害剤です。 EGFR-IN-9 には抗腫瘍活性があります。
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Cas No.: 1226549-39-8
Sample solution is provided at 25 µL, 10mM.
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EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1].
EGFR-IN-9 (Compound 8) shows antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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