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7,3',4'-Tri-O-methylluteolin

カタログ番号GC35184

7,3',4'-トリ-O-メチルルテオリン (5-ヒドロキシ-3',4',7-トリメトキシフラボン) は、フラボノイド化合物であり、LPS 誘導マクロファージ細胞株において、炎症メディエーター、NO、PGE2、および炎症誘発性サイトカインの放出。

Products are for research use only. Not for human use. We do not sell to patients.

7,3',4'-Tri-O-methylluteolin 化学構造

Cas No.: 29080-58-8

サイズ 価格 在庫数 個数
1mg
$87.00
在庫あり
5mg
$171.00
在庫あり
10mg
$261.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) is a flavonoid from the herb Lippia nodiflora L. (Verbenaceae) which has been documented to exhibit anti-inflammatory, antipyretic, antitussive, antidiabetic, anticancer, and antimelanogenesis properties. 7,3',4'-Tri-O-methylluteolin obviously reduces the prodn of pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-1β in a concentration-dependent manner. 7,3',4'-Tri-O-methylluteolin significantly induces reduction in the mRNA expressions of inducible nitric oxide synthase and cyclooxygenase-2, representing that inhibition occurs at the transcriptional level[1]. TNF-α IL-6 IL-1β

[1]. Sudha, A, et al. Protective effect of 5-hydroxy-3′,4′,7-trimethoxyflavone against inflammation induced by lipopolysaccharide in RAW 264.7 macrophage: in vitro study and in silico validation. Medicinal Chemistry Research, 2016,25(9), 1754-1767.

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Average Rating: 5 ★★★★★ (Based on Reviews and 3 reference(s) in Google Scholar.)

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