HG-14-10-04 |
| カタログ番号GC36222 |
HG-14-10-04 は、ALK、EGFRLR/TM、EGFR19del/TM/CS、EGFRLR/TM/CS の IC50 がそれぞれ 20 nM、15.6 nM、22.6 nM、124.5 nM の強力な ALK および変異型 EGFR 阻害剤です。 HG-14-10-04 は抗がん剤の研究に使用できます。
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Cas No.: 1356962-34-9
Sample solution is provided at 25 µL, 10mM.
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HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: ALKMore information can be found in the following Patent, Example 10Preparation of substituted pyrimidinamines as ALK kinase inhibitorsBy Aquila, Brian; Kamhi, Victor; Peng, Bo; Pontz, Timothy; Saeh, Jamal Carlos; Thakur, Kumar; Yang, Bin From U.S. Pat. Appl. Publ. (2012), US 20120028924 A1 20120202.
[1]. U.S. Pat. Appl. Publ. (2012), US 20120028924 A1
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