SY-1365 (Synonyms: SY-1365) |
| カタログ番号GC37709 |
SY-1365 (SY-1365) は、17.4 nM の Ki を持つ、強力でファーストインクラスの選択的 CDK7 阻害剤です。 SY-1365は、固形腫瘍細胞株において抗増殖およびアポトーシス効果を示します。 SY-1365 は、血液および多発性進行性固形腫瘍において抗腫瘍活性を有します。
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Cas No.: 1816989-16-8
Sample solution is provided at 25 µL, 10mM.
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SY-1365 is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors[1]. CDK7
[1]. Hu S,et al. Discovery and characterization of SY-1365, a selective, covalent inhibitor of CDK7. Cancer Res. 2019 May 7.
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