Protein Kinase C 19-31 (Synonyms: PKC (19-31)) |
| カタログ番号GC37014 |
プロテインキナーゼC（PKC）のペプチド阻害剤であるプロテインキナーゼC 19-31は、PKCaの偽基質調節ドメイン（残基19-31）に由来し、25位のセリンが野生型アラニンに置き換わっています。プロテインキナーゼC活性をテストするためのプロテインキナーゼC基質ペプチド。
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Cas No.: 121545-65-1
Sample solution is provided at 25 µL, 10mM.
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Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins[1][2].
[1]. Mellor H, et al. The extended protein kinase C superfamily. Biochem J. 1998 Jun 1;332 ( Pt 2):281-92. [2]. Nishizuka Y (1995). Protein kinase C and lipid signaling for sustained cellular responses" (abstract). FASEB J. 9 (7): 484-96.
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