Vat-Cit-PAB-Monomethyl Dolastatin 10 |
| カタログ番号GC38480 |
Vat-Cit-PAB-Monomethyl Dolastatin 10 は、ADC リンカー Vat-Cit-PAB を介して結合された Monomethyl Dolastatin 10 (強力なチューブリン阻害剤) を使用することにより、強力な抗腫瘍活性を持つ ADC の薬物-リンカー結合体です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1415329-13-3
Sample solution is provided at 25 µL, 10mM.
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Vat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.
[1]. Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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