3,4-Dimethylmethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry) (Synonyms: 3,4DMMC metabolite)

3,4-Dimethylmethcathinone (3,4-DMMC) (hydrochloride) ((±)-pseudoephedrine stereochemistry) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, a psychoactive compound that has been identified in products sold as bath salts and plant food.1,2,3 This metabolite of 3,4-DMMC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.

References
1. Gibbons, S., and Zloh, M. An analysis of the 'legal high' mephedrone. Bioorg. Med. Chem. Lett. 20(14), 4135-4139 (2010).
2. James, D., Adams, R.D., Spears, R., et al. Clinical characteristics of mephedrone toxicity reported to the UK National Poisons Information Service. Emerg.Med.J. 28, 686-689 (2011).
3. Jankovics, P., VÁradi, A., T•lgyesi, L., et al. Identification and characterization of the new designer drug 4'-methylethcathinone (4-MEC) and elaboration of a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method for seven different methcathinone analogs. Forensic Science International (2011).