Leukotriene A4 methyl ester (Synonyms: LTA4 methyl ester) |
| カタログ番号GC18835 |
ルコトリエンA4（LTA4）は、5-リポキシゲナーゼ（5-LO）によってアラキドン酸からマスト細胞、好酸球、および好中球で合成されます。この酵素はリポキシゲナーゼとLTA4合成酵素の両方の活性を示します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 73466-12-3
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.
Review for Leukotriene A4 methyl ester
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
Review for Leukotriene A4 methyl ester
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *