Lysosphingomyelin (d18:1) (Synonyms: D-erythro Lyso SM(18:1), D-erythro-Sphingophosphorylcholine, D-erythro Sphingosine-1-Phosphocholine (d18:1), Lyso-SM(d18:1), Lysosphingomyelin (d18:1)) |
| カタログ番号GC44105 |
スフィンゴミエリンは、ホスホリルコリン、スフィンゴシン、脂肪酸などのアシル化されたグループから構成される複雑な細胞膜脂質です。
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Cas No.: 1670-26-4
Sample solution is provided at 25 µL, 10mM.
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Sphingomyelins are complex membrane lipids composed of phosphorylcholine, sphingosine, and an acylated group, such as a fatty acid. Lysosphingomyelin is a naturally-occurring lipid which is produced by the removal of the acylated group of sphingomyelin by a deacylase. Lysosphingomyelin may, in turn, serve as a substrate for autotaxin, which removes choline to produce sphingosine-1-phosphate. The receptors and signaling pathways that are activated by lyso-sphingosine are diverse and vary between cell types. Lysosphingomyelin occurs naturally in plasma, is a constituent of lipoproteins, and is increased in some diseases, including dermatitis and Niemann-Pick disease.
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